PTEN and breast carcinoma: The same TFA-based analysis on Netherland Cancer Institute (NKI) published breast cancer dataset that does not have associated PTEN status [36], also classifies breast cancer in three subgroups, and the Group 1, predicted to be PTEN negative, is associated with poor differentiated, ER-negative basal-like phenotype [37] (Figure S3B), which is consistent with our recent publication [38].