However, cells specific for NY-ESO-1 and for MAGE-A10, two other tumor-antigen specific T-cell populations with lower precursor frequencies, were comparable to Melan-A-specific T-cells regarding the expression of inhibitory receptors, arguing that higher TIM-3 and PD-1 expression and lower CD160 expression is a general feature of self/tumor-specific T-cells. Here, MLANA is linked to neoplasm.