Furthermore, a statistically significant decrease in expression of the inner mitochondrial membrane peptidase 2-like (IMMP2L) [24], [25] gene was also observed in BACHD (p≤0.05) and FVB (p≤0.01) striatum following wig-1 ASO treatment, which has been linked to a possible rare cause of Autism and Gilles de la Tourette syndrome (GTS) [25]. The gene discussed is ZMAT3; the disease is autism.