CDK4 and neoplasm: Table 1 lists the fold changes in tumour cell intensity in binary logarithm relative to normal tissue intensity. Upregulation of PFTK1 expression was noticeable in tumour tissue compared with the normal tissue (fold change 2.607, P<0.001, Figure 1). Significant upregulation was also noted in CDK1, CDK4, and CDK18 (CDK1: fold change 1.316, CDK4: 1.391, CDK18: 1.450; P<0.001, each) whereas significant downregulation was evident in CDK7 (fold change −1.436, P<0.001).