To further define a role for NOD2 in BD with pulmonary manifestations, we analysed NOD2 mRNA transcriptional responses in BAL (broncho-alveolar lavage) and PBMC (peripheral blood mononuclear cells) harvested from BD patients with pulmonary manifestations, sarcoidosis patients (disease controls) and healthy controls. The gene discussed is NOD2; the disease is Behcet disease.