Recent analysis using surgical specimens suggested that mesothelial cells may nurture peritoneal metastases through the production of growth factors such as vascular endothelial growth factor (VEGF) and fibroblast growth factor 2 (FGF2) [35], confirming Wilson's finding that mesothelial cells from ovarian cancer patients were able to stimulate the clonogenic growth of ovarian tumor cells [36]. This evidence concerns the gene FGF2 and ovarian neoplasm.