In compare to the mesenchymal stromal cells (HOTC) of normal ovarian tissue, we have shown that mesenchymal like cancer tumor fibroblasts (HOCTC) sprouting from ovarian cancer tissue expressed higher levels of BMP2, BMP4 and TGF-β, which are highly associated with tumorigenesis and metastasis. The gene discussed is BMP4; the disease is ovarian carcinoma.