INS and myeloid sarcoma: Although recent definitions of MS do not include direct measurement of insulin in children (Eyzaguirre and Mericq 2009), insulin resistance (IR) has been frequently reported to overlap with MS and to confer cardiometabolic disease risk distinct from that attributed to MS itself (Haffner et al. 1990; Dhuper et al. 2007; Steinberger et al. 2009).