In our study, the inhibition of ATM in cervical cancer cells interfered with the irradiation-induced G1 and G2/M cell cycle arrest, in line with the loss of checkpoint function in cells from patients with AT.4, 7, 30 ATM inhibition furthermore severely decreased clonogenic survival for all tested cervical cancer cell lines, indicating that cervical cancer cells heavily depend on the ATM signalling axis for survival after irradiation. Here, ATM is linked to cervical carcinoma.