CTHRC1 and colorectal neoplasm: Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of CRC since they have shown an increase messenger RNA transcripts (mRNA) expression level in colorectal tumours when compared with normal tissues [9-12].