The course of PbAluc infection in control, α-PD-L1- and α-CTLA-4-treated mice (Figure 4A–C) was similar to the course of PbA infection (Figure 3A–C), confirming that insertion of the luciferase gene had not significantly altered the basic biology of the parasite, although the onset of ECM was slightly delayed (α-CTLA-4-treated mice developed ECM on day 10 post infection; α-PD-L1-teated mice developed ECM on day 11 and control mice were euthanised on day 18). Here, CD274 is linked to infection.