PINX1 and nasopharyngeal carcinoma: As shown in Tables 4 and 5 and Figures 7 and 8, overexpression of Pin X1 by transfection of pEGFP-C3-PinX1 significantly reduced hTERT mRNA level by 21% and decreased telomerase activity in NPC 5-8 F cells (p = 0.000).