Certainly, this inhibition was only partial, which indicates that other activating receptors, such as NKp30 or NKp46 (moderately expressed by our NKL cells) might also be contributing to the tumor cell lysis or that the numbers of anti-NKG2D antibody (at the blocking concentrations used) were not sufficient to block all the receptors remaining on the cell membrane. This evidence concerns the gene KLRK1 and neoplasm.