However, while susceptibility to MBP- and MOG-induced EAE in HLA-Tg mice was determined by the DRB1*1501 allele of the HLA-DR15 haplotype, the previously reported susceptibility to PLP91-110 epitope was associated with the DRB1*0301, a non-Caucasian MS-associated allelic gene of the HLA-DR3 haplotype. This evidence concerns the gene MOG and myeloid sarcoma.