GRN and neoplasm: A final pair of multivariate analyses incorporating GP88, age, ethnicity, tumor size, tumor grade and disease stage (Table 7) further demonstrated that GP88 remained an independent prognostic indicator for both DFS and OS as shown by the fact that HR for GP88 adjusted for all the other indicators remained unaffected and significant (HR = 5.15 with P < 0.0001 for DFS and HR = 1.8 with P = 0.0148 for OS).