IL33 and cryohydrocytosis: Furthermore, stratification of patients with CHC revealed that the concentrations of serum IL-33 in CHC patients with abnormal levels of serum ALT (>50 units/L) or AST (>40 units/L) were significantly higher than those in CHC patients with normal levels of ALT (<50 units/L) or AST (<40 units/L), respectively (P < 0.001, P < 0.001, resp., Figures 1(b) and 1(c)).