AKT1 and cancer: An increasing number of studies have reported that GTCs, especially the major biologically active component in green tea (−)-epigallocatechin gallate (EGCG), inhibit proliferation of and induce apoptosis among cancer cells by modulating the activities of different receptor tyrosine kinases (RTKs) and their downstream signaling pathways, including the Ras/extracellular signal-regulated kinase (ERK) and PI3K/Akt signaling pathways [17–19,73,74].