NFKB1 and xeroderma pigmentosum: NF-κB-dependent HIV-LTR activation required lower doses of UV-C (2 J/m2) in cells from patients with Xeroderma pigmentosum group A (XPA) than in cells from healthy human individuals (20 J/m2), which supports the idea that DNA damage is required for proper NF-κB activation [76].