In addition, inhibition of p38 and ERK in a squamous cell carcinoma cell line SCL-1 has been shown to inhibit UV-A and UV-B-induced matrix metalloproteinases MMP-1 (stromelysin-2) and MMP-10 (interstitial collagenase) expression both in vitro [103] and in vivo [104]. Here, MAPK1 is linked to squamous cell carcinoma.