Carriers of the C/T of rs3804099 and rs3804100 of TLR2 had a nominally significant association with decreased HCC risk (OR 0.493, 95% CI 0.331 - 0.736; OR 0.509, 95% CI 0.342 - 0.759) by age and sex adjustment (P < 0.01) (see Table 3) compared with T/T carriers. The gene discussed is TLR2; the disease is hepatocellular carcinoma.