To our knowledge, the association between the CYP11B2 c.-344C>T polymorphism and the extent of atherosclerosis in CAD has not been reported; however the CYP11B2 c.-344C>T polymorphism has been related to the severity of atherosclerotic plaque size in the carotid artery (Sharma and Katz 2010). This evidence concerns the gene CYP11B2 and coronary artery disorder.