While therapy with pCEA was not able to induce responses to reduce the growth of tumors in comparison with the control group, mice in the CEA-SARS-CoV group exhibited significantly less tumor growth, indicating that the SARS fragment provided adequate protection against CT26/CEA (Figure 4, p < 0.05 in comparison with the control and the pCEA group). The gene discussed is DDX53; the disease is neoplasm.