A Kaplan-Meier plot showed a prominent difference in survival estimates for patients with high versus low Oct-4 expression in tumor tissue; this difference corresponded to a median survival of 18.2 ± 6.0 months for patients with high Oct-4 expression compared with a median survival of more than 24.7 ± 9.1 months for patients with low Oct-4 expression (Figure 3A). The gene discussed is POU5F1; the disease is neoplasm.