In this analysis, we used organ-specific antibodies, including TTF-1 for lung cancer, WT-1 or PAX8 for gynecological cancers, mammaglobin or GCDFP-15 for breast cancer, PSA for prostate cancer, CDX2 for gastrointestinal cancers, and uroplakin for urothelial cancers. The gene discussed is TTF1; the disease is Familial prostate cancer.