Detection of hemoglobin by the o-dianisidine staining on embryos of p53+/+nola1+/?; p53+/+nola1−/−; p53−/−nola1+/?; p53−/−nola1−/− showed that the anemia observed in nola1 mutants was rescued in the p53 null background (Fig. 3D, arrows). This evidence concerns the gene TP53 and anemia (phenotype).