ADRB2 and autonomic dysreflexia: Mechanisms for autonomic dysreflexia that have been considered include upregulation of vascular catecholamine receptors, increased neural release of catecholamines, decreased pre-synaptic reuptake of catecholamines, loss of the baroreceptor reflex, altered glutamatergic control of spinal neurons and loss of tonic bulbo-spinal inhibitory input to spinal neurons [8].