We previously reported [9] that the Thomsen-Friedenreich (TF; Galactose-β-(1 → 3)-N-acetyl-D-galactosamine) antigen, which is displayed on cell-surface proteins and lipids in 70% to 90% of adenocarcinomas of the breast [10], is upregulated in post- (but not pre-menopausal) women with breast atypia and cancer, correctly classifying either cancer or abnormal vs. benign pathology 83% of the time in postmenopausal women. The gene discussed is TF; the disease is cancer.