“Sensitive” cell lines have total growth inhibition (TGI) between 0.1 and 1 μM, while “resistant” cell lines are refractory to Bz and AF concentrations <10 μM. Among the consistently sensitive cell lines to both compound classes were the ER(+) breast cancer cell lines MCF-7 and T47D [18, 19]. This evidence concerns the gene ESR1 and breast carcinoma.