To investigate the pattern of neutrophil in carcinomatous and non-neoplastic human colorectal tissues, we conducted IHC staining of CD66b on a CRC-TMA containing 229 pairs of primary CRC specimens and corresponding normal colorectal mucosa, and on 30 samples (whole tissue slides) of CRC lymph node metastasis. This evidence concerns the gene CEACAM8 and colorectal carcinoma.