Because the population of U937 cells with high EVI1 expression (U937/EVI1) in the G0-phase was increased on the matrigel-coated plates compared with those on the BSA-coated plates (Fig. S5), the increased quiescence of adhered EVI1high AML cells might be one of the reasons for resistance to anti-cancer drugs. This evidence concerns the gene RUNX1 and acute myeloid leukemia.