CACYBP and neoplasm: At the 5th week, the average tumor volume in the MKN45-pFLAG group was 776.9±90.9 mm3, which is significantly more than that of the MKN45-CacyBP group (578.9±51.2 mm3) (P<0.05), and even more than that of the MKN45-ΔS100 group (364.9±71.9 mm3) (P<0.05) (Fig. 4C).