Although CD151 overexpression did not show any impact on survival in regard to AJCC stage I cancer, CD151 overexpression had a significant influence on OS in stage II cancer (CD151-high vs CD151-low, 117.3 months (95% CI, 106.2–128.4 months) vs 135.6 months (95% CI, 131.7–139.5 months), P=0.0474) and stage III cancer (CD151-high vs CD1515-low, 86.7 months (95% CI, 70.9–102.5 months) vs 110.4 months (103.1–117.7 months), P=0.0169) (Figure 2B). This evidence concerns the gene CD151 and cancer.