Taking the median of CRP values (2.7 mg/dl) to divide patients into two subgroups, 10 patients with CRP≥2.7 mg/dl had infections whereas 20 patients did not have signs of infection (6 patients with unknown trigger of TMA, 5 patients post-partum, 3 patients with tumour, 3 patients with drug-induced TMA, 2 patients with SLE). The gene discussed is CRP; the disease is systemic lupus erythematosus.