We incubated murine bone marrow derived dendritic cells (BMDDCs) with CC13, GPIC, C. muridarum Nigg or CM3.1 to determine if dendritic cell cytokine release was altered by the loss of the plasmid from C. caviae and to compare cytokine release during infection with C. caviae or C. muridarum. The gene discussed is RBM39; the disease is infection.