The top marker (rs1341665, p = 2.82×10−16, 0.692 mg/L average increase per G allele) is in strong LD with several variants, including rs1205, a 3-prime flanking region SNP previously implicated in CRP expression and systemic lupus erythematosus susceptibility (Table 1 and Table S1) [26]. Here, CRP is linked to systemic lupus erythematosus.