How HCMV infection induces CaMKK activity still remains to be determined, although it has previously been reported that HCMV infection induces Ca2+ release from ER stores and we have found that HCMV infection induces CaMKK expression [16], [44], both of which would be predicted to increase CaMKK activity. Here, CAMKK2 is linked to cytomegalovirus infection.