Interestingly, Choi et al. [76] recently reported that patients with GBA-associated synucleinopathies showed aggregation of oligomeric forms of α-synuclein in SDS-soluble brain fractions, while only monomeric forms of α-synuclein were present in subjects with GBA mutations without parkinsonism. This evidence concerns the gene GBA1 and synucleinopathy.