In an interesting case report, Assadi described a pregnant woman with HELLP syndrome (hemolysis, thrombocytopenia, elevated liver enzymes) and elevated circulating levels of TNF-alpha, whose newborn baby had nephrotic syndrome that resolved postnatally [37]; although the baby received hydrocortisone, the authors argue that transient proteinuria was most likely the result of transplacental TNF-alpha, since levels of the cytokine fell in parallel with resolution of proteinuria. This evidence concerns the gene TNF and nephrotic syndrome.