IL4 and malaria: The administration of IPTi-SP did not significantly affect the proportion of CD3+ cells producing intracellular IFN-γ, IL-4 or IL-10 in peripheral whole blood samples stimulated ex-vivo with P. falciparum extract antigens, at any of the time points, neither by unadjusted analysis nor by adjusting for previous episodes of clinical malaria (Table 1).