Similarly, higher concentrations of plasma IFN-γ (IRR 1.15, 95% CI 1.05-1.27, P = 0.0040) and MCP-1 (IRR 1.60, 95% CI 1.22-2.10, P = 0.0007) at 12 months were associated with higher malaria risk during the 12-24 month period. The gene discussed is CCL2; the disease is malaria.