Re-analysis of changes in Ang-2 levels after treatment and of Ang-2 levels in clinical subgroups at screening using Ang-2 levels adjusted for the effect of low GFR changed only one of the conclusions to be drawn from Tables 1, 2, and 3: subjects with active GN no longer had higher values than subjects with active AAV without GN (median 2.8 vs. 2.5 ng/ml, P = 0.33). This evidence concerns the gene ANGPT2 and ganglioneuroma.