CCR2 and neoplasm: Figure 1A shows a CCCD camera photography of a representative control (CCR2+) mouse (a) compared to CCR2−/− mice (b), and analysis of mean total flux (photons per second) of all six mice within each experimental group (Fig. 1B). These results show a highly significant difference between both groups (5.81×104±0.7 compared to 1.93×104±0.09, p<0.001). Notably, the decreased luciferase activity in tumors implanted in CCR2−/− mice was not associated with a significant decrease in tumor size, as measured by caliper (Figure 1C).