As shown in Figure 6d, injection of CD44/Sca1+ tumor cells resulted in the detection of 4.99 ± 0.5%, 1.77 ± 0.3%, and 3.56 ± 0.9% GFP and ESA double positive (GFP/ESA+) cells in the blood, LN and lungs, respectively, of recipient mice. The gene discussed is CD44; the disease is neoplasm.