CDH1 and breast carcinoma: To achieve this, a chemically inducible form of E-cadherin was introduced into MDA-MB-231-luc-D3H2LN breast cancer cells (henceforth known as 231LN) (Figure 1B), which express negligible levels of endogenous E-cadherin similar to the parental MDA-MB-231 cell line (data not shown) [22].