As shown in Figure 1, a statistically significant (P<0.05) upregulation of LEDGF/p75 transcript was observed in prostate (2.38 fold, P = 0.002), thyroid (1.85 fold, P = 0.031), breast (2.26 fold, P = 0.037) and colon (2.04 fold, P = 0.047) cancers. The gene discussed is PSIP1; the disease is cancer.