POLG and testicular cancer: Interestingly, a study of CAG repeat polymorphisms in the POLG gene in testicular cancer showed 36 (74%) wild-type homozygotes and 13 (26%) lacked one or both wild-type alleles, with the 10/11 variant in 10 patients and the 10/12, 10/6 and 11/11 variants in one patient each, suggesting that variants of the DNA POLG1 gene were more frequent in testicular cancer patients than in healthy men [12].