ATM and cancer: Intriguingly, the ATM rs664677 polymorphism showed evidence of an association with an increased risk for breast cancer (dominant model comparison: OR = 1.447, 95% CI = 1.203–1.740), but demonstrated a protective role in the development of lung cancer in the meta-analyses stratified by cancer type (dominant model comparison: OR = 0.764, 95% CI = 0.635–0.918; Figure 3b).