From the literature, we know that in the presence of high-plasma glucose levels FDG uptake is enhanced in cardiac and skeletal muscles [4] and in vitro studies indicate that FDG accumulation in cancer cells will decline with increasing glucose levels [5] and, similarly, in tumours of rodents, a decrease of the mean FDG uptake has been observed at very high blood glucose and insulin levels [6]. This evidence concerns the gene INS and neoplasm.