The role of GSTP1 is debated in literature for example Zschenker et al.[39] reported a no statistically significant reduction in G2/G3 fibrosis (like-protective), Kuptsova et al.[40], also in analyzing breast cancer patients found no difference for fibrosis due to the relative small number of patients with this side effect. The gene discussed is GSTP1; the disease is breast carcinoma.