The flow cytometry analysis indicated that over-expression of PDCD4 induced cell cycle arrest mainly at G1 stage; 1.2 (p< = 0.01) and 1.8 (p<0.01) fold increase in the percentage of the cells at G1 stage in OVCA433-PDCD4 and SKOV3-PDCD4 ovarian cancer cells, respectively (p< = 0.01). This evidence concerns the gene PDCD4 and ovarian cancer.