RGS5 and hydrops fetalis: At initial of feeding, the markers of inflammation and lipid profiles were no difference among the groups except FFA (Table 2); However, after 24 weeks of feeding, fasting plasma triacylglycerol, cholesterol and LDL levels were significantly higher in RGS5 KO mice than in WT mice fed an HF but were not distinguishable between genotypes in mice fed an NC (Table 3).