For example, binding motifs for E2F and Fox family members, including FOXO1 (FOXO1A), FOXA1 (HNF3A), and FOXF2 (FREAC2,4), are highly enriched in PR-binding sites in breast cancer cells but not in leiomyoma cells (Table S2). The gene discussed is FOXA1; the disease is leiomyoma.