By comparing the expression level in different tissues (17 cases of normal lung tissues, 18 cases of lung adenocarcinoma tissues and 15 cases of metastatic lymph nodes), we found that the expression of ABCE1 mRNA and protein in cancer tissues were higher than in normal tissues (p<0.05) and lower than in metastatic lymph nodes (p<0.05) (Tables I and II). This evidence concerns the gene ABCE1 and lung adenocarcinoma.